“We’re starting now to uncover long-term consequences of COVID-19 that literally will last a lifetime,” Dr. Al-Aly noted, at least one is related to inflammation. Of the issues long COVID patients experienced, Dr. Louis, Missouri, spoke about long COVID in a Show Me the Science podcast. Ziyad Al-Aly, the director of Clinical Epidemiology at the Washington University School of Medicine in St. “Our findings of persistent systemic inflammation, particularly in those in the very severe and moderate with cognitive impairment clusters, suggest that these groups might respond to anti-inflammatory strategies,” says Professor Louise Wain, one of the study authors and professor in the Department of Health Sciences at the University of Leicester.ĭr. While the authors write that the mechanisms behind long COVID are unknown, they hypothesize that the hyper inflammation associated with COVID-19 dysregulates the immune system. She also notes that females and people with obesity may “need higher intensity interventions such as supervised rehabilitation.” Rachael Evans, clinical associate professor and honorary consultant respiratory physician at the University of Leicester in the United Kingdom. ![]() “The limited recovery from 5 months to 1 year after hospitalization in our study across symptoms, mental health, exercise capacity, organ impairment, and quality-of-life is striking,” writes lead author Dr. The researchers found that many of the people who were on mechanical ventilators in the hospital did not feel fully recovered after 1 year.Īdditionally, the prevalence of not being back to full health was higher among females and participants with obesity. Of the participants who came back for a 1-year follow-up, 28.9% felt fully recovered, which is an improvement of only roughly 10%. ![]() The majority reported not feeling recovered from COVID-19.Īt the 5-month follow-up, 25.5% of the patients reported feeling fully recovered. Of the participants who completed their 5-month follow-up, 807 completed a 1-year follow-up appointment. Half of the participants fell into the very severe and severe clusters. The researchers assigned participants to four clusters depending on the severity of their physical and mental health symptoms: very severe, severe, moderate, and mild. Doctors also tested the participants’ cognitive abilities and pulmonary function. The patients completed questionnaires about anxiety, depression, fatigue, post-traumatic stress disorder (PTSD), and other health issues. ![]() The participants followed up with their doctors 5 months after being released from the hospital to have their symptoms assessed. All participants were originally hospitalized due to COVID-19-related illnesses. The researchers started with a group of 2,320 participants who were discharged from the hospital between March 7, 2020, and April 18, 2021.
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